October 30, 2021

Life: Covid booster mix and match Pfizer, day 2

 My worksite is a hospital complex. Sick people gather in hospital, which makes my workplace a high risk place for covid. 

That is why they set up covid vaccine and booster clinic as early as on October, right after booster is approved, along with annual flu shot clinic. On 10/21, CDC expanded booster eligibility, and the expansion covered me. Now I can get booster.


Today, my worksite's president was announcing covid vaccine mandate for all employees. (To clarify, booster is not included in the mandate). I have no objections for the mandate.


On early Feb, I got Moderna vaccines, completing the series. It has been almost 9 months. It may be prudent to get the booster now. So I scheduled covid booster on this past Wednesday (2 days ago).


I am curious if mix and match (using vaccines from different makers) work better than sticking to single source. On paper, they said mix and match gave a good deal of boost in neutralizing antibody amounts. In theory, I anticipate some differences in mRNA sequences between Moderna and Pfizer mRNA vaccines. Mixing them may add some variety to the practice targets (mock covid/spike protein) for my immune system to work up, and it may be better in terms of preparedness for real covid infection.

I can't go beyond speculation unless there are 100 of me and I can set up cohorts of me with proper controls and collect datasets and compare. I'll skip idle reasonings here.


I got Pfizer booster on Wed. I was somewhat concerned that I might have rough side reactions like the 2nd dose, which knocked me out for 48 hours. Just in case, I bought milk and chicken soup cans beforehand.

But overall, my reaction to the booster shot was much milder. By the night, the injection site was aching, but I felt ok. I slept through the night, no problem. 

The next day (Thursday) I woke up with sore muscles (like I had a good exercise), sore throat, and some dullness. But it was not like real sick feeling. Lack of headache, fever, or exhaustion really helped. I went to work. 

Today (Friday) the sore was subsiding. Generally I felt better than yesterday. Probably my reactions to the Pfizer booster shot would be gone by tomorrow.


Now is end of October 2021 (10/29/2021). Personally, I don't feel like preaching importance of booster shot any more, and feel like I'd rather leave the preaching job to some others who are still willing or are in the position to do it as a public official. There are people who already know the importance and will get or have gotten booster. And there are people who listen to entirely different news and information source that I call Tabloid "journalism". These people may or may not be keen with booster, or even the first dose(s) of vaccination. 

Outbreak of delta variant in Aug-Sept 2021 clearly indicated the difference between these two people. One lived their lives and managed. The other also lived their lives, quite a few of them got severe covid and occupied ER and ICU almost selectively. They were the ones who clogged up medical system. They tried horse med (Ivermectin) instead of vaccine, like they did not learn a thing from the malaria med (hydroxychloroquine) saga. Isn't ignorance a sin.


I completed covid vaccines with Moderna, and got a Pfizer booster. I am using latest modern medicine that 2021 can offer, and I am very happy about it. 

2020 and 2021 are different, in terms of our arsenal against covid. Halloween is another opportunity to remember death. Today may be a good time to remember all the death from covid, and do something about it (...hmm am I preaching?).

For the laughs, I have not been able to receive or sense 5G broadband yet.








October 18, 2021

Life: October is Breast Cancer Awareness month.

October is Breast Cancer Awareness month.

An easy thing to do is to wear something pink to help the awareness movement. It serves the purpose if someone gets mammogram, quits smoking, revises diet, changes lifestyle, or however creates environment that goes toward stopping cancer (that does not have to be limited to breast cancer, but whatever) or makes patients' and their family's lives easier.


[even something subtle like watch strap or wrist band should be fine]

For people who like something more tangible, there are some fundraising events like "Real Men Wear Pink" by American Cancer Society (which is legit, in case you are cautious), and you can contribute to it.


Besides, (unfortunately), it may not be difficult to find your link with breast cancer. 


Based on NCI's estimates, about 44,130 people (43600 female, 530 male) in the US are predicted to die of breast cancer in 2021. They are not a small number. Although lung cancer is the biggest killer with 131,880 deaths, which is followed by colorectal cancer with 52,980 deaths and pancreatic cancer with 48,220 death, breast cancer makes the 4th in cancer deaths.

In terms of new cases, breast cancer is the biggest among all cancers (281,550 female 2,650 male).


For me personally, I had two friends who died of breast cancer in her 30's and 40's. Their lives were cut short.

My sister got one several years back. I don't really see any cancer in my family, so it was one of freak sporadic case. She went through surgery and chemo and is alive fine now. I am thankful for her survival. 

My postdoctoral research was funded by DOD breast cancer research program. It helped my career and I am also thankful for that.


You may or may not be a person who pays attention only when it hits close to home. Yet, it would be important to be reminded of this cause. 

"October is Breast Cancer Awareness month."






October 1, 2021

Life: Two "cancer report" mangas from Japan (Why there is no such useful/educational essay mangas in the US?)

 I picked up two "cancer report" mangas in Japanese Amazon.

[By Hirunama (left) and by Ruri Fujikawa (right)]


Many mangas are "graphic novels" that tell long fictions, like Naruto, Dragon Ball, Demon slayer (Japanese), or Marvel comics (US). But there is a category in manga called "essay manga". The two mangas I picked up are by two mangakas each of whom got cancer in her 30's (one stage 4 colon, one stage 1b ovarian), went through surgery and chemo, and is alive to tell her own cancer story in essay manga format. 


I found them quite informative in terms of what happens in cancer treatment from the standpoint of a patient. Also, they can be quite real and emotional.


In an episode, the mangaka befriended with a roommate (Mrs. A) in her hospital. Later, Mrs. A let her know that she would stop treatment, implying that her cancer is beyond treatment. Two months later, Mrs. A's husband let the mangaka know about Mrs. A's passing. 

The mangaka brought some sweets to Mrs. A's altar. Mrs. A's diet was restricted due to GI tract obstruction. They talked about the sweets to have, once their cancer treatments are done.

Sometimes, it is something "real" like this that hits you. We don't always need an outrageous Hollywood epic story to feel it.


In the US, this kind of manga seems non-existent, while I found at least several of this kind of manga in Japanese Amazon.  

Maybe because manga is not as common in the US as in Japan. Maybe the number of mangaka is much less in the US than in Japan. Maybe just "essay manga" format is less known.

Cancer patients are there both in the US and in Japan. But not everyone can report their experience in the manga format. Of course, there are publications on survivors' recounts and advices for cancer patients in the US. As a person, US patients may be using blog or other ways (or not to talk about "the c-word" at all).


As a format, manga has to be visual. The format is naturally presented objectively, if not theatrically. Professional mangakas are trained to tell stories in the format.

While, writing on survivors' recounts tend to be narratives or train of thoughts, with less consideration for how they look. Not everyone is trained to talk about their experience in an objective manner, anyway.


Real stories told by professional narrators with communication in mind (mangakas). No wonder these essay mangas are so effective. 

Someone in publication business in the US should consider publishing this kind of essay mangas for medical education or liaison to public.



I picked them up thinking that they may help my professional learning on how cancer treatments are done in clinic and how they are perceived by patients in real world. 

I got to admit, my reading motivation is not always from pure curiosity. But I've learned a lot. 

They were actually entertaining in an unorthodox way, too. I enjoyed reading them both.